Usually different from just about anyone else (I've limited strength and dexterity with my right hand).
It varies between cameras.
My Olympus XA - upside down so I can squeeze it between my left thumb (on the release) and my left middle finger. My right hand serves as a side brace.
My OM bodies - the right bottom is cupped in my right hand, while my left hand stretches over the top of the pentaprism so that my left index finger can reach the release. I wind with my right thumb. I adjust focus, aperture and shutter speed with the left hand.
With my Canon EOS bodies I'm forced to use my right index finger to release the shutter. That is sometimes a frustrating challenge, because that is at the extreme edge of my right hand's dexterity. The left hand is below the camera and supports the weight.
The Retina IIIc is held and the shutter is released in the same way as the Canons. I find it slightly easier to reach the shutter release with the right index finger.
All three of my Mamiya platforms - 645 Pro, C330 and RB67 work easily with the left hand trigger grips.
In many cases, I tend to have to do a lot of switching things around to make adjustments to focus, aperture and shutter speed . In some cases, I have to do that to wind the film too.
After doing if for 50 years or so I'm pretty good at all that switching around to make those adjustments, but I can't compete with most people when it comes to fast operation.