Ok I have some samples for you to decide for yourself. I have found a 35mm photo that I enjoy first. All the test images were scanned at 1200 DPI at image size so .89 in x 1.38 in. The last is a 100% crop of the image scanned at 12.30 x 19 @ 400DPI (I figure that would be closer to printing size you asked for.) The film is Agfa APX 400 developed in 1+75 Rodinal based on my "secret timing..." Which involves a whole bunch of guess work... lol
Here is the basic image
Here is no tone adjustments with just the USM box. From top to bottom they are; no USM, Med, and High
Here is my "artist rendition" (which would probably change each time I scan it unless I scan to TIFF but thats another thread)
As you can see the amount of USM is up to you and with just the untoned image you can do a lot in photoshop using only the dodge and burn tools, Levels, and Curves. A little note, for all of my images I have done some selective sharpening other wise the grain is to wide spread.
Dead Link Removed
This last image is a 100% crop of the 12.30 x 19 @ 400DPI after using "auto exposure, USM low, Dust removal low," and adjusting the levels and curves in PS. As a Jpeg on disk it is about 5mb but once opened in PS it is 106mb.
Hope this helps point you in the right direction for now. MF will come if you would like to see more examples with the large negative. The ultimate key is how big you want to print them. If you just want to post them on the web increasing the DPI to 1200 will be more then enough for any size negative. If you want to Print though you have to select the "target size" and then change the DPI accordingly. Also don't forget that if you want to crop within the images then the target size should be larger. My optimum settings are going to differ from yours because of how I like my images to look. So where you might use High USM all the time I might never use more the low. This scanner is pretty much amazing and with an optical DPI of 6400 I think it can scan and print for just about any size you want (depending on the viewing distance). again another thread another time.
Sit down, play with your scanner at different settings to see what the images look like and then play with them again once you are ready to print. I usually call my printing company and ask them if they will give me some kind of deal on printing about 5 images to "calibrate" my new equipment. Last time I was sent 5 8x10's for the cost of shipping.
Enjoy,
~m