Sacrifice a couple of sheets and do tests. Just pull one out and then look at it, as suggested above. I've had problems with the anti-halation layer on the non-emulsion side of some films being defective. I had to toss a couple of 25-sheet boxes of BPF-200 because of this shortly before they stopped making the film. There were bubbles/separations on the non-emulsion side; not sure if it was caused by the interleaving paper, moisture or just age degradation. Check the emulsion side for defects, mold, abrasions, etc. as well. Look at the interleaving paper and see if there are any artifacts there too.
If nothing is evident from visual inspection, then develop an unexposed sheet and see if the defects are somehow in the emulsion. If so, you can develop your way through the stack, hoping that only a few sheets are affected.
Best,
Doremus