Weight can be an issue. I happen to really like the 350 "C" T*
I've had mine quite awhile and the thing is extremely durable. Seems much better built than the newer CF series. The lens shoots gorgeous chromes and I don't Hesitate for a second to recommend it. The hood is compatible with the 500mm, which I also have. So, I have a arsenal of 250 - 500. The 350 being a great equalizer when I don't want to lug around the weight of several long lenses. The 350 is a great lens for fashion too.