I haven't got a Hasselblad 100mm, but I can say the obvious about my shooting experiences with both cameras:
Rolleiflex: Light, quiet, lovely, great handheld but awkward on a tripod
Hasselblad: Heavier but manageable, versatile, good handheld but better on a tripod
Negatives won't know the difference, both are capable of more than 99% of photographers, I'd guess.
If you want a 'longer' feeling, I would suggest looking at the 120mm Makro(or S)Planar. It provides the most "wow" factor of any lens I have used. If you want a true MF telephoto experience but can't cough up for an 180mm, the 250mm's are plentiful and quite cheap (esp. in C variant).
If you aren't attached to 6x6/Zeiss, I'd look at the Pentax 67 and 165mm 2.8 and/or 105 2.4.