Jesus, tough crowd. I have an idea of how guide numbers work, and could do it manually if circumstances permitted. However, I want to take candid pictures. If flash power is going to require constant adjustment based on distance to the subject, that's not a great solution. I would much rather be thinking about composition and interacting with subjects than computing distances and guide numbers or waving around an incident meter. That said, I plan on buying a flash with manual control, and probably eventually picking up a flash meter. Obviously, that provides more precise control than you could get in any automatic mode, and I assume that after you've been doing it for a while, you begin to pick up a more intuitive grasp of how it all works.
*edit* Perhaps I should rephrase that -- I'm not necessarily looking for candid pictures, but I do want to maintain a certain informality. I am, after all, taking pictures of friends and family.