I don't know if Epson scanners are more susceptible to dust than other scanners but I kind of doubt it.
I rarely use digital ICE because it has not been all that effective for me. I typically dust everything very thoroughly before I start, as I progress, and even at the end. But I know I will still have to do some dust spotting if I decide I want to PP a given scan. If the one I decide I want to work with is really dusty I will sometimes scan that negative again.
I use a V500 and I dust the lid glass, the bottom glass and the anti-newton glass. Then I pass the film strip through an anti-static brush. I usually keep the film strips inside the PrintFile sleeves until just before I scan. Dust is a PITA but it is an unavoidable part of the process.