First, I will assume you would use a excellent (and expensive) scanner. The answer then depends on the print you want and to some extent on the negative. It may also depend on how much time and experience you have. Some manipulations are much easier to do in Photoshop than in the darkroom, but the reverse is also true. Some things are only practical in Photoshop unless you have very extensive darkroom experience and special supplies and equipment. The darkroom is generally more fun, and it is a bit cheaper. The learning curve (for ordinary work) is about the same in difficulty for either, but the techniques are quite different. The resulting prints also look quite different, and your choice may well depend on which look you like better. You have a somewhat wider range of surfaces for digital printing, and that may be a factor, too. For prints that require some manipulation (but not all that much), digital printing may be somewhat faster (but not all that much). Scanning negatives at high resolution is a slow process, and the resulting files are very large. Storage for these files is a major consideration. Scanned negatives also usually need considerable spotting. That is easy in Photoshop, but it is tedious. For large prints from reasonably large negatives, enlargements are usually a bit sharper. Modern digital printers do an excellent job, and I use that method for most of my color prints (despite improvements, black and white is still not as good as darkroom prints). But the darkroom has certain advantages, and it is much better for people who think in those terms.