I wouldn't consider this to be a big mystery. Roll film - both 35mm and MF -comes in a rather sterile package, and the only time it is exposed to dust in the environment is while it is in the camera or being processed.
LF film, by contrast, has to be loaded into holders which are then carried around in some kind of container until the film is exposed, and again until it is taken out of the holders for processing. That additional exposure to the environment means that it is has lots of opportunity to pick up more dust.
LF photography requires an almost anal approach to the disciplines required to achieve the quality that the process is capable of. Care has to be taken to assure that the humidity is right when holders are loaded and unloaded - if the air is too dry, dust will be attracted to the holders. Holders must be impeccably clean. Always brush out (and preferably vacuum) holders before loading. And just before putting a loaded holder into the camera to make an exposure, use a small brush to remove any dust that might be clinging to the outside of the holder. Careful workers (and I admit that I don't do this) put their holders into zip-lock bags to protect them from dust as soon as they are loaded, and again immediately after exposure. If a changing bag is used in the field for loading or unloading holders, care has to be taken to assure that it does not become the source for dust getting into holders.