I know you are into ULF, and if cost is an issue, I assume you are implying somethign larger than 4x5?
For anything larger than, arbitrarily, 4x5, I'd be concerned about flatness, rigidity, etc. It flexes pretty easily and while it may have been due to the protective paper (although it is on both sides), I have seen acrylic that did not sit flat.
I previously had concerns about using it for viewing in view cameras...same physical issues for using it as plates.
An experiment with a small piece won't cost much & may work just fine!