The optics don't change-- a 100mm lens with a 25mm aperture is going to be a 100mm f/4 lens, regardless of what size focal plane is being used.
If used with a 35mm full-frame camera, and an APS-C 1.6x crop factor camera, then the only difference should be that one produces a 36x24mm image, and the other produces a 22.3x14.9mm image. But the 22.3x14.9mm rectangle at the center of the image should be identical on both cameras.
Similarly, if that lens can cover 6x7 negatives, then if used with a 35mm camera, you should have a 36x24mm rectangle at the center of the 6x7 negative that exactly matches the negative captured on a 35mm camera.