I like Diafine with conventional films. It doesn't work nearly as well, in my experience, with tabular films though it does "work" it just doesn't get the kind of effective speed increase it does with some older films. I have used it with TMY at EI 640 IIRC.
Diafine negs can tend to look flat but print well, often with slightly higher paper contrast than conventional negatives. It is compensating so will tend to tame, or compress depending on whether you want the effect or not, highlights. It may be expensive - it isn't cheap here now either - but it lasts and lasts and lasts. I used to get 70 rolls or so through a quart. It's actually very economical per film, even at high prices.
That said, HC-110 is not expensive per film either given the dilutions and the concentrate lasts and lasts, at least. Bottom line - very different developers.