Here's what I did when I used trays to process 4x5 film. (I've been using a Jobo CPP-2 and expert drums for quite a while.) Use 8x10 trays for 4x5 film in the following order: water, developer, stop, fix and hypo clear. Put about 1-1.5 L of liquid in each tray. Get all the solutions as close to your developing temp as possible. Hass intellifaucets are neat
. Place a negative one at a time emulsion down in the water tray. Hold the negative by the edges with your left hand if you're right-handed. With your right hand, take one of the negatives by the edges. Lower your hand until your little finger touches the water, and then drop the negative emulsion side down into the tray, keeping the negative as parallel to the water as possible. You'll hear a little plop as the negative hits the water. Push the negative to near the bottom of the tray using your little finger. Don't get your other fingers wet. Quickly but carefully do the same for each negative. (I usually did 6 to 8 negatives, but use less to start.) Once they're all in, shuffle the negatives by using your left hand to keep them in the lower left corner of the tray. Take your right hand and slide the bottom negative away from you as far as you can in the try, pulling the negative up and out of the developer at the end. Take that negative and drop it onto the lower left corner of the tray as before, making sure that the other negatives have been pushed bellow the surface of the water with your left hand. Repeat. Shuffle the negative for 2 minutes and then pick them up and place them in the developer tray. Start your timer. A foot switch really helps. Immediately start shuffling as before. This time, though, go through the whole stack once and then shuffle one more negative. Now rotate the whole stack 90 degrees clockwise. keep doing this for the entire developing time. So if you have 5 sheets of film, shuffle 6 negatives and then rotate. This will make sure that the bottom negative isn't always the same one, which could cause it to have more agitation than the others. 15 seconds before the end of the time. Pick up the whole stack and drain a bit. Place the stack in the stop bath when the time is up. Shuffle. ....
The emulsions should always be down. That way, if you make a mistake and drop a negative such that it's corner digs into one that's in the water, you'll only be hitting the base side of the film with the corner. It also means that when you pull out the bottom negative, you won't scrap the emulsion against the edge or corners of the stack.
Arrange your developer temp and dilution such that your development time is about 10 minutes. That way small differences in development time, such as caused by each sheet getting introduced to the developer at a slightly different time, will make very minor changes.
Make sure your trays do not have sharp bits on them. Sometimes they have little nubs left over from the casting process. If so, use a razor blade or sand paper to smooth them out.
Practice at least once with 4 sheets of film with the lights on. That'll really help you get a feel on how to do it correctly.