I have both LowePro and ThinkTank backpack/roller cases that will hold and protect 'everything'... but, for their outrageous cost (both around $400.), they do neither backpack NOR roller job very well. I love Pelican cases for the protection but they are just TOO big & heavy to move! I love Domke's canvas bags, but there wasn't much protection for gear, plus they're expensive (though I do still use my Domke vest).
So lately, I've been having fun trying to find 'alternative' camera bags. It's no secret that many new photo bag models are 'hiding' the camera bag look, so why not do that yourself and save money? I love to look thru thrift stores 'cuz you'd be amazed at what people get rid of... old rucksacks and daypacks that are large enough to hold a modern padded case (or even two) and yet don't have that 'STEAL ME' vibe! I've found both black & brown real leather rucksacks, as well as a very cool, 'Ol Skool' cotton canvas & leather day bag, that have more usable room than I generally need for 1 cam + acc stuffed inside a padded camera bag stuffed inside the outer bag... and yet cost less than $10. or $15. (often a LOT less). Yes, it's a bit more trouble to go digging though stuff to find these treasures at Goodwill, but isn't that part of what we love about old film cameras in the first place? Btw, on my profile, there's a photo of my new 'army issue' mini Alice bag that holds all of my 6x9 Mini Speed Graphic kit (protected by a LowePro bag fitted inside). Go have some fun and think outside of the 'camera' bag!