Try and make your initial tests by varying the aperture. You could try something like 10 seconds, with an f/stop range of f/4 to f/16. Any decent lens will have a reasonably consistent change from f/stop to f/stop. Avoid older lenses, especially those which don't have click stops, or the really old ones which don't have a consistent spacing between f/stops. Don't use an aperture between f/stops, unless it is also click-stopped; you'll never hit the same spot twice.
The trick here is to pick a negative which is truly representative of your average shooting conditions. If you shoot mostly, say, under daylight, don't use a negative which was exposed to a mix of tungsten and fluorescent light! You can make a series of negatives, which were exposed under the typical conditions you might use when photographing. You could have a daylight exposure, a tungsten exposure, a fluorescent exposure, a mixed lighting exposure, et cetera.
A good idea would be to make an exposure of series of exposures, with a flesh tone and a gray card. Avoid colour bars, or Macbeth Color Checkers, as the colours are somewhat too saturated to make a judgement call on colour balance. The flesh tone and gray card should be adequate.
Make a range of exposures, from about three stops under to three stops over. Measure the gray card densities using a calibrated densitometer, and compare them to the maufacturer's specs. If you don't own a densitometer--most photographers don't--ask the manager of the laboratory where you have your colour film processed if you can use theirs. You can also pick and "over" and "under" negative for future comparison. I assume you don't process your own film; that's a mechanical operation best left to a laboratory.
Use the same film stock, preferably from the same emulsion number, for your test, as you purchase for day-to-day use. Yes, it DOES matter; if you haven't the financial wherewithal to buy a large stock of film of one emulsion, when you buy film, bring a carton of the old film and ask for the same emulsion number.
If you want further information on this subject, drop me a PM.