Different? How's this...
If you haven't gone up 1 to SF, then by all means drive it. I have many times in every kind of weather you can imagine. It is a wonderful drive. But, during the summer it is also very "touristy."
Maybe leave the ocean view drive for something off-the-beaten-path with some interesting sites and stunning beauty in a different way. I have done this drive many times too, and it is a wonderful experience.
Drive N only to Ventura and then head inland on 33 to Ojai (home of the Six Million Dollar man.) Follow 33 into the mountains. Great photo ops all along the way and most of the time there is very little traffic. After about an hour of so you will run into 166, turn right (this is 166/33).
After coming down Banner grade into beautiful "old west" scenery you will hit Maricopa. A little oil town with lots of history. This is where 166 and 33 split up again (at the stop sign). Turn L at the stop sign and stay on 33.
The next town you hit will be Taft. A not-so-little oil town. It is also the scene of many films: Five Easy Pieces, The Best of Times, and others. To stay on 33 you have to turn L into town or you will find yourself on 119 heading to Bakersfield.
As you go N on 33 you go through some not-so-pretty but interesting scenery such as thousands of oil pumps rocking as far as the eye can see. You eventually get to 46 (Pasa Robles Hwy) where you can turn L and head to 101/1 again. This is where James Dean was killed.
I, however, would keep heading N on 33. You will be riding the road pretty much alone for miles (which is what I enjoy.) You will eventually hit Coalinga where you will run through town and continue N on 198. I have only gone this way once, but it was fantastic. A little road running through beautiful canyons and farms. When it hits 25, you can stay on 198 and hit the 101 or turn right onto 25 and continue on this great little lost road and eventually hit Hollister.
I like off-the-beaten-path. I don't like highways. This jaunt from Ojai to Hollister will be wonderfully devoid of traffic. I love it. The scenery isn't the stunning beauty of 1, but is it something everyone should see.