Hi,
Depends what you mean by "actively using"! I have an ESII, ES and first of the series the Electro Spotmatic. I don't use them all the time, but from time to time I take each out for a bit of exercise. Not so much this year, of course, for obvious reasons. Mechanically, they are very well built but what let them all down even when relatively new was the electronic circuitry, which was not exactly the last word in reliability. The ESII was the last and probably best of the bunch. That said, most of the faults are fixable. My ESII was giving inconsistent exposures when I bought it but a repairer I used at the time cured the problem and it has been fine ever since (must be about 20 years). The ES had two problems which I found myself - a bad soldered joint and a problem with the electromagnet that (IIRC) releases the second shutter curtain. The Electro Spotmatic also had a bad soldered joint. I think the electronics were basically OK but just not rugged enough.
As has been said, the meter doesn't work in manual mode but you can set it to auto, see what shutter speed is indicated for a given aperture then go back to manual. The marked manual shutter speeds from 1/60th to 1/1000th work independently of the batteries or meter.
Unless the camera has been thoroughly checked by someone who knows what they are doing or it's warranted, I would assume that any of the ES series probably won't work. If you pay accordingly (there are lots of them out there) and it works, so much the better but if it doesn't, have the cash put by for a service/repair. When working properly all are nice cameras to use, delivering remarkably good auto exposures.
Best wishes,
Steve