Not easy to tell because the paper imparts its own pronounced 's' shape on the overall tone reproduction cycle that can overwhelm whatever is going on with the negative tonal separation. In general, however, a negative exposed on the toe (where the shape is upswept) will have not so good shadow separation compared to the same scene exposed on the straight line. But if you are talking about the resulting prints on photographic paper, the difference may not be as great as you would expect.