Which lens are you having this problem with? My G1 never had any difficulty w/ the 50 lens, but the 90 was a different story. I had to practice w/ it by pointing it at different things and seeing exactly where the camera thought the focus point was.
You can manually focus the lens too, but I think it involved going into the menu so I never did that. Lots of people have had focus issues w/ the G1 cameras, but in my case it was just understanding how it worked best w/ that 90 Sonnar.
They're also known to have focus issues if there isn't good connectivity between the camera's lens mount and the lens. See if you have any bluish stuff there. If so, clean everything well, and make sure the batteries are full voltage and the contacts are clean.