The Jobo drums give a minimum volume for one-shot print development, but that is usually low for film developers that are less concentrated (generally).
My experience doing 8x10 in print drums is that a) make sure the drums are completely dry inside before loading them. A drop of water running around pre-development will show up, and b) make sure the drum is completely level when it is on the rollers. If you are using a multiple segment drum assembly, make sure all the segments are fully seated - a 'bent' assembly will cause standing waves.
If you load a sheet the opposite way (but still emulsion towards the centre), are the density marks in the same place compared to the end of the drum?
If the marks are due to different turbulence around the join in the locating ribs, my first suspicion would be insufficient solution.