Bronica 6x6 SQ systems with a 645 back attached will crop the top and bottom of the image projected by the lens, giving you a landscape format when the camera is held in normal shooting position. Like Matt mentioned, shooting in portrait format is easier if you have a prism finder, versus the waist-level finder. With a speed grip and the prism finder, it's actually like holding a 35mm SLR, just a lot heavier.
The focusing screens on my SQ bodies have lines for 645 framing, so no need for a finder mask.
If you're doing low light / night shooting, I would look for an SQ-A body as it has mirror lockup and slow speeds down to 8 sec. For exposures longer than 8 sec, there is a "T" lever on the lens which opens the shutter as long as you need with no battery drain. I've used mine for night shooting for years and it's always worked great. I've heard that the SQ-Ai bodies go thru batteries quicker, but I can't vouch for this. My SQ-A has been going on the same battery for a few years now.
If you're sure you only need 645, may as well look at the Bronica ETRs also. The available lenses give about the same coverage as the lenses for the SQ, but will be smaller and lighter overall. The bodies and all other accessories will also be smaller, which will be easier if you're shooting handheld.