I probably do most of my work with 6X9, and some with 4X5. I basicly agree with Roger's remark. There is a definite improvement as you go to the larger formats, but the really big jump is going from 35mm to 645. The advantage of the 645 format is the availability of small, easy to use SLR cameras. They offer all the convenience of 35mm along with the advantages of the larger negative size. Although the Pentax 67 SLR is an excellent camera, its bulk begins to slow you down. Good rangefinder cameras are available in 6X7, 6X9, and even 4X5 that are pretty fast and convenient, although lens interchangeability and viewfinder use suffers some, particulaly close to the subject.