I do not process very often ( except recently I seem to be ), so I leave my chemistry is their concentrated form and not dilute until I run a roll. I also purge the concentrates after use ( I use Argon, just because I also have it for welding ).
For any given kit, I look at the kit capacity, pick a number of rolls that I would be happy with. The point here is what you are happy with. Most kits have a stated capacity, most kits can process more rolls than that.
From there, when I process a single roll, I figure how much concentrate to mix into the volume of chemistry I need to process that single roll.
Example ( Using Bellini C-41 kit ), it states 16 x 24 exposure rolls of 35mm. Because I mix fresh each time and use one shot, I decided to try for 15 rolls of 36 exposure.
My tank needs 140ml of chemistry, to mix full working strength would take 66ml of developer to make 140ml of chemistry. The kits first developer comes with 260ml of concentrate, so using one shot I would only get 7 rolls processed.
What I did was take the 260ml and divide that by the 15 rolls I want to get out of the kit, so I mix 17ml of the developer to make 140ml.
From there I look at the processing times vs number of rolls processed. In the Bellini kit it showed for rolls 13-16 to use 4:00. So that is my starting point.
I do the same for the bleach and fix, divide the concentrate ml by the number of rolls I want to get out of it. For the bleach and fix I double the standard times.
I have just started using the Bellini kits and so far are working well, I have not adjusted my development time yet.
I do the same with the Bellini E6 kit with similar results.
Now, If I run multiple rolls, things get better, the chemistry I mix gets closer to the "normal" ratio.
I have been doing it this way for over 30 years using Kodak, Tetenal, Arista, and other chemicals with the same results, The film I processed 30 years ago has not faded or otherwise done something odd.
My concentrates have lasted as short as a few months to over a year, It has always been visually obvious that a developer is dead.
Back to my Optima film, it is a bulk roll of Optima 100 I bought many years ago. I shot it at "box" speed and processed as mentioned above. I also have some Provia 100F that is about 10 years old with no negative effects.