I think a 2-color monopack would be awesome. I asked PE about it, and he said it would be 'relatively' easy to do with dye-bleach. Emphasis on 'relative'. Dye-bleach is used in cibachrome, and the idea is to utilize the silver image as a catalyst for the reduction or oxidation of the dye present in the emulsion. No color couplers, no controlled diffusion, or other complicated processing techniques. One would only need 2 layers, one sensitive to blue and the other to red, and two appropriate dyes to form a bluish-green & orange image. I believe that the chemicals required aren't very exotic or hard to find.
No one ever marketed an integral, 2-color monopack, AFAIK, because by that point why would you settle for 2-color when you could have 3. This original Kodachrome can't be considered 'integral' in my opinion because the processing requires that you float either side of the dual-sided film on toning baths.
edit: Reading the patent 1196080, it seems that it wasn't toned, but simply dyed. And it wasn't the duplitized film stock, my bad. But that being the case, it seems like any dye that can be used in dye-imbition could be used, as it only requires a differential reaction to tanned & untanned gelatin to form the dye image.