If you are serious about an 8x10 and want to enlarge, take a look at enlarger options before moving forward. In all cases, they are huge. They either need a lot of height or are horizontal. I've shot a fair amount of 4x5. It isn't all that heavy to haul around compared to medium format. 8x10, on the other hand, is pretty big and heavy. Also, remember that is isn't just the camera......those film holders add up pretty fast both in weight and in bulk. The tripod needs to be that much bigger too. All that said, 8x10 has 4x the film area of 4x5 and that will make a significant difference if you regularly need to make 50" prints. The question is whether the increased quality is worth the much higher cost and complexity.