I usually remove my glasses when using the R3A. Yesterday, though, I forgot to leave my glasses in my car, so I was stuck with them. I found that I could fairly easily see the 50mm framelines, however, I had to hunt for the shutter-speed readout. I seriously doubt that one could see the 40mm framelines with glasses.
I'm fortunate, though, in that my eyeglass prescription is pretty weak, so I tend to shoot without my glasses on. Right now I'm hunting for a diopter for my R3A.
It may be a bit of a PITA for the moment, but seriously, that 1:1 VF is the sweetest thing I've ever used and it's all worth it.
Kent